The Clan Curse of the Brujah is their uncontrollable temper. Most records agree that the Clan Curse was the retribution from Caine for Troile's diablerie of his sire, Ilyes. The Erciyes Fragments state: "He who claimed innocence because/the Beast ruled him/shall be slave to the Beast forever".

Bahari myths tell that [Brujah] was cursed by Lilith along [Tzimisce] and [Set], when they slaughtered Lilith's children. Old texts speak of an argument between Troile and his/her (the records are unclear about Troile's exact gender) sire that escalated and ended with Troile's diablerie of his sire. For this, he was cursed by Caine: "Never before has one of my progeny drunk the very soul of another. I curse you ever to aspire your sire's wisdom, but also to be prey to the very diabolic fury that drove you to this act." These texts tell that Troile accepted Caine's punishment and assumed his sire's name to honor what he once had been. Other comment that the tendency to frenzy arouse only after the fall of Carthage and is their founder's legacy for his surviving progeny for forsaking him in his final battle. Some Baali claim that the origin of the Brujah curse is their shame at their collaboration with the Devils in Carthage and their knowledge that all their aspirations to erect the Third City fell when they prostituted their ethics away for power and legend. The Followers of Set remember the True Brujah, who were created by Thoth and placed under the sign of the Libra, and believe that the aggression of the modern Brujah stems from their failure to live up to their founder's legacy.